36 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g. celiac disease ... Advanced Liver Disease ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Disorientation, vertigo Diagnostic ... test, TempTest ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... LungDisease #CTILD #Diagnosis ... #Differential #Comparison ... #Table #Pulmonary ... #Rheumatology #
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... MAHA: TTP, HUS, DIC ... Drug-associated, PCH ... Laboratory Tests ... #hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
inhibitor • Liver disease ... • Factor XI, IX ... • Underfilled test ... Thromboplastin #laboratory #hematology ... #diagnosis
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... syndrome Anti-Scl ... (TTG) - Celiac disease ... #diagnosis #table ... #rheumatology #
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Elevated Liver tests ... schistocytes, DIC ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Elevated Liver tests ... schistocytes, DIC ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
suspicion of severe disease ... and these should ... splenomegaly, abnormal neurology ... Rheumatology ... Peds #Pediatrics #Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... symptoms - Pel-Ebstein ... Differential Diagnosis ... #oncology #diagnosis ... #differential #hematology