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differential management erythematosus comparison disease systemic dermatology msk syndrome workup ana antinuclear approach associations autoantibodies classification cppd criteria myopathy myositis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... lesions • Discoid lupus ... #joint #pain #skin ... #differential #diagnosis ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Pain Eyes ... Heberden's nodes (DIP joints ... #pain #differential ... #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: ... of hip (rare), Arthritis ... lesions Abdominal pain ... signs #symptoms #diagnosis ... #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Pain History ... both at rest and ... improves quickly with rest ... #Pain #MSK #rheumatology ... #differential #diagnosis
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... INVOLVING 2 OR MORE JOINTS ... Direct Coombs’ test ... #Rheumatology # ... SLE #Lupus #Erythematosus
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Rheumatica • Pain ... with temporal arteritis ... Diffuse muscle pain ... #differential #diagnosis ... #comparison #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
common sites: hip, shoulder ... dz difficult to see ... Osteomyelitis / Septic Arthritis ... #differential #diagnosis ... #causes #hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
• Arthritis domain ... in at least 2 joints ... Classification #Criteria #SLE ... Erythematosus #diagnosis ... #rheumatology
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