11 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , others (RNP, aPL ... Anti-cardiolipin (aCl ... Anti-centromere, Scl ... Autoantibodies #Rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... conditions - Sp-100, PML ... #differential #diagnosis ... #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... Score • CML -> AML ... smear: Blasts APML ... #Leukemia #Hematology ... #Oncology #Diagnosis
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... conditions • Sp-100, PML ... #differential #diagnosis ... #rheumatology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... Acute • Myloid (AML ... T-cell - CD7, CD3 Chronic ... Blood #Disorders #hematology ... #Differential #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Incidence: common in APL ... fluid overload, PCC ... Differentiation #Syndrome #APML ... #hematology #oncology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Atopic diseases, Chronic ... doi: 10.1111/all ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... adults in the west ... Transform to DLBCL, PML ... #workup #oncology ... #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... should be obtained ... for Chronic Polyarthritis ... (to support a diagnosis ... #testing #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... Differential Diagnosis ... La, anti-Jo-1, SCL ... with Lupus: • Chronic ... #Rheumatology