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diagnosis lupus causes erythematosus hematology systemic ana antinuclear druginduced autoantibodies management medications table abnormal aptt classification coagulation diseases patterns prolonged
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... disease (MCTD), Drug-induced ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology ... #diagnosis #differential
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Thrombocytopenia - Differential ... methotrexate) • Drugs ... Autoimmune • ITP • SLE ... Alloimmune • anti-HLA antibodies ... Algorithm #Causes #Hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
disease (MCTD), Drug-induced ... Idiopathic Arthritis, Drug-Induced ... Biliary Cirrhosis, Drug-Induced ... ANA #patterns #rheumatology ... #diagnosis #differential
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
RA Anti-dsDNA - SLE ... Anti-histone - Drug-induced ... SLE Anti-Jo-1 - ... diagnosis #table #rheumatology ... #antibodies
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
involvement 3% SLE-Related ... Auto-Antibodies ... Lupus Mimickers: Drug-induced ... Lupusreference #SLE ... #rheumatology
Lupus Classification Spontaneous Lupus - Cutaneous Lupus Erythematosus (CLE) - Systemic Lupus Erythematosus Drug-Induced Lupus - Drug-Induced
Erythematosus Drug-Induced ... Lupus - Drug-Induced ... - Drug-Induced ... erythematosus #rheumatology ... #diagnosis #differential
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... terbinafine, thiazidic, PPI ... Erythematosus (SLE ... comparison #table #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... Anti-histone (in drug-induced ... SLE) • Systemic ... Antineutrophil #antibodies ... #diagnosis #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... (60-70%) & drug-induced ... Anti-Ribo-P 5-15% If SLE ... higly specific for SLE ... erythematosus #diagnosis #rheumatology
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Drug Induced Systemic ... associated with drug-induced ... #pharmacology # ... risk #differential ... #diagnosis #rheumatology
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