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diagnosis hematology syndrome lupus algorithm erythematosus workup cardiology disease systemic nephrology neurology oncology dermatology pharmacology pulmonary thrombocytopenia anemia antibody checklist
Thrombotic Microangiopathies In Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE ... #hematology #rheumatology ... #differential # ... diagnosis #causes
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - SLE ... Scl70 (in some cases ... Scl-70 (in some cases ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... for decreased PLT ... test, ANA (e.g., SLE ... Platelet #Disorders #Differential ... #Workup #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Positive in 60-80% of cases ... life-threatening • Treatment ... Usual therapeutic management ... #Summary #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Autoimmune • ITP • SLE ... Diagnosis #Algorithm #Causes ... #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
• Blood smear: Differential ... 2) LOOK FOR a cause ... Anemia #diagnosis #management ... #treatment #rheumatology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... • Special cases ... #Measurement #SLE ... #rheumatology # ... levels #lupus #management
Diagnosis and Treatment of Common Causes of Pulseless Electrical Activity (PEA) #Pulseless #Electrical #Activity #PEA #Differential #Diagnosis
Diagnosis and Treatment ... of Common Causes ... Activity #PEA #Differential ... #Diagnosis #Management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
• Specific for SLE ... severe disease Treatment ... Erythematosus #SLE ... Summary #diagnosis #rheumatology ... #management
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