11 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... 60 (Ro60), SSB (La ... , PBC/SjS OS ... #Patterns #differential ... #diagnosis #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Diagnosis Algorithm ... Lymphocytic Leukemia (CBC ... #LAD #Differential ... #Causes #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... activity • ↓ LAP ... count • ↓Hg & PLT ... #Leukemia #Hematology ... #Oncology #Diagnosis
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
60 (Ro60), SSB (La ... pattern: • SSc, PBC ... dots pattern: • PBC ... #differential # ... diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... count: CBC(.plateletcount ... smear, HIV/HCV testing ... - Lab for decreased ... #Workup #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... initiation • Differential ... fluid overload, PCC ... Differentiation #Syndrome #APML ... #hematology #oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Acute • Myloid (AML ... ALL) - PAS, TdT Lymphadenopathy ... (+) ↑ WBC
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
or "S" shaped nuclei ... • Stab cell - nucleus ... especially in the setting ... #Bandemia #differential ... #WBC #CBC #hematology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Putrid sputum/sour-tasting ... : • CBC - Leukocytosis ... CXR upright or lat ... Lung Abscess Differential ... Abscess #pulmonary #differential
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
+Organomegaly+↑RBC ... /plt+, ↑thrombosis ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology