22 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... Algorithm Acute ... - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... Blood #Disorders #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Diagnosis: • ... • Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Diagnosis: • Pancytopenia ... Treatment: • Consider ... stem cell transplant ... progress to MDS or acute ... #treatment #hematology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
sickle cell hepatic ... Supportive with treatment ... hepatomegaly and anemia ... Hepatobiliary #hepatology ... #differential #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Infectious: • Acute ... or Chronic Inflammatory ... effect following treatment ... Iron deficiency anemia
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential Diagnosis ... Thrombocytosis): • Acute ... malignancies • Anemia ... myeloid leukemia (CML ... #Causes #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
deficiencies: Chronic ... Index > 3: • Acute ... defects (e.g. sickle cell ... Production #Index #hematology ... #diagnosis #calculation
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute ... Allogeneic stem cell ... #Management #treatment ... #hematology #oncology