17 results
hematology oncology management algorithm differential causes syndrome aplastic leukemia mds myelodysplastic thrombocytosis apml cancer cell chronic classification cll coagulation criteria
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... #Algorithm #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Diagnosis: • Pancytopenia ... Treatment: • Consider ... progress to MDS or acute ... #diagnosis #management ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute ... only curative treatment ... #Management #treatment ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Infectious: • Acute ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... High in acute blood ... for degree of anemia ... #Algorithm #Diagnosis ... #Workup #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... changes), high MCV anemia ... #Causes #Workup ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... • Rare: DAH, acute ... Renal Failure Treatment ... fluid overload, PCC ... #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • ↓ WBC • ↓ PLT ... Treatment: ... #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... #workup #oncology ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... + Bleeding Treatment ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
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