44 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
• Reticular/AMA ... /SjS OS - AMA ... ARUPConsult @ARUPLabs #ANA ... #differential #diagnosis ... #rheumatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
) - Summary PBC ... intralobular bile ducts causes ... progresses • +AMA ... 1.5 x ULN • AMA ... #workup #hepatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Disease Associations ANA ... Anti-mitochondrial (AMA ... biliary cirrhosis (PBC ... Associations #diseases #diagnosis ... #table #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... old, ~10,000 new cases ... acute leukemia Management ... #Management #treatment ... #hematology #oncology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Patterns Reticular/AMA ... PBC/SSc OS, PBC/ ... SjS OS • AMA Speckled ... #differential #diagnosis ... #rheumatology
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
Causes of ileitis ... See below for table ... www.ncbi.nlm.nih.gov/pmc ... articles/PMC2914216/ #Diagnosis ... #Differential #Table
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
opacities • Diagnosis ... fluid overload, PCC ... coagulopathy, RRT/IMV as ... #management #hematology ... #oncology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
reported (eg AIH-PBC ... , AIH diagnosis ... : Auto-Nuclear ANA ... Hepatitis (eg Viral) Management ... #Management #Hepatology
Predicting an anatomically and/or physiologically challenging airway is not a straightforward task by any stretch of
and/or physiologically ... may not be as applicable ... emergency airway management ... #Diagnosis #EM # ... PCC #Heaven #Criteria
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
cryoglobulinemia vasculitis - Diagnosis ... , causes and management ... anti-infectious therapy as ... Cryoglobulinemia #Vasculitis #Rheumatology ... #Management