32 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
: - SSc, PBC/ ... : - PBC, DM, ... , PBC/SSc OS, PBC ... #differential #diagnosis ... #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... old, ~10,000 new cases ... cytopenias (usually anemia ... #Management #treatment ... #hematology #oncology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
: • SSc, PBC/SSc ... : • PBC, DM, other ... ARUPConsult @ARUPLabs #ANA ... #differential #diagnosis ... #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
PBC, SSc, PBC ... /SSc OS, PBC/SjS ... ARUPConsult @ARUPLabs #ANA ... #differential #diagnosis ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... changes), high MCV anemia ... or if a primary hematologic ... #Differential #Diagnosis ... #hematology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
asymptomatic at diagnosis ... of UDCA for all patietns ... #Cholangitis #diagnosis ... #management #summary ... #Hepatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential Diagnosis ... Cold AIHA • PCH ... immune-complex hemolytic anemia ... #Hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and ... Disease Associations ANA ... biliary cirrhosis (PBC ... Associations #diseases #diagnosis ... #table #rheumatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
hepatocellular pattern ... though cholestatic pattern ... reported (eg AIH-PBC ... : Auto-Nuclear ANA ... #Management #Hepatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... petechiae Causes ... • ↓ WBC • ↓ PLT ... #oncology #hematology ... #diagnosis #management