20 results
differential testing antinuclear treatment autoimmune comparison cytoplasmic dermatology hepatology nuclear summary syndrome aih anemia antibodies antinxp2 antinxp2dm aplastic apml associations
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... , PBC/SSc OS, PBC ... ARUPConsult @ARUPLabs #ANA ... #differential #diagnosis ... #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... : • SSc, PBC/SSc ... : • PBC, DM, other ... #differential #diagnosis ... #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
• PBC, SSc, PBC ... /SSc OS, PBC/SjS ... SjS, SLE, RA, PBC ... #differential #diagnosis ... #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Disease Associations ANA ... biliary cirrhosis (PBC ... disease Endomyseal antibody ... Associations #diseases #diagnosis ... #table #rheumatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
asymptomatic at diagnosis ... of UDCA for all patietns ... #Cholangitis #diagnosis ... #management #summary ... #Hepatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... old, ~10,000 new cases ... acute leukemia Management ... #Management #treatment ... #hematology #oncology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
hepatocellular pattern ... though cholestatic pattern ... reported (eg AIH-PBC ... : Auto-Nuclear ANA ... #Management #Hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
opacities • Diagnosis ... • Differential Diagnosis ... fluid overload, PCC ... #management #hematology ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... gastric tumors • Hematology ... #differential #diagnosis ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Cytopenia +++ (Plt ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
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