14 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... fluid overload, PCC ... #APML #diagnosis ... #management #hematology ... #oncology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
of Pregnancy (AFLP ... ) Three syndromes ... child * Severe cases ... #obstetrics #hematology ... #diagnosis #table
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - PBC ... , SSc, PBC/SSc OS ... , PBC/SjS OS ... #differential #diagnosis ... #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management ... old, ~10,000 new cases ... Myelodysplastic #Syndrome ... #hematology #oncology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
biliary cirrhosis (PBC ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... • ↓ WBC • ↓ PLT ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Organomegaly+↑RBC/plt ... WAIHA • CAD • PCH ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology