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management differential algorithm rheumatology dermatology anemia gastroenterology hemeonc leukemia neurology syndromes workup aplastic arterial bowel cancer cardiology chronic cirrhosis classification
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Causes Intravascular ... ) - HELLP syndrome ... hemoglobinuria (PNH ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential Diagnosis ... • PCH • PNH ... #Algorithm #Causes ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... (MD) - Diagnosis ... old, ~10,000 new cases ... #MDS #Diagnosis ... #hematology #oncology
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
disorders • Diagnosis ... and Treatment Algorithm ... Matthew Ho, MD ... #HES #Hematology ... #eosinophils #diagnosis
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... - Differential Diagnosis ... - Disseminated intravascular ... neoplasms - PNH ... #clots #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
- Differential Diagnosis ... • Iron loss: Intravascular ... Gastrectomy, WHDA syndrome ... Matthew Ho, MD ... Algorithm #ferritin #hematology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... : • Facial edema ... #differential #diagnosis
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Differential Diagnosis ... - Water - Pus ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... #differential #diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Symptomatic anemia Diagnosis ... Can progress to MDS ... • Associated PNH ... #management #treatment ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Matthew Ho, MD ... #Algorithm #hematology
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