31 results
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... - Differential Diagnosis ... artery aneurysm: Causes ... neoplasms - PNH ... #clots #hematology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid ... Indications and Pharmacology ... increases venous & arterial ... TXA #Tranexamic #Acid ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology ... #differential #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... deficiencies - PNH ... gangrenosum • Bacterial ... #Differential #Diagnosis ... #hematology #rheumatology
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
rule out other causes ... metabolized to lactic acid ... branched chain amino acids ... #Management #treatment ... #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... myalgias, HoTN, edema ... Renal Failure Treatment ... #management #hematology ... #oncology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... with pulmonary edema ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
Presence of pulmonary arterial ... other obvious causes ... pressure < 15mmHg TREATMENT ... - Mechanism: causes ... #management #hepatology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Summary A defect in arterial ... lung disease Caused ... ) on room air Treatment ... #management #treatment ... #hepatology