14 results
diagnosis management differential syndrome dermatology mds myelodysplastic thrombosis venous activation anemia antinxp2 antinxp2dm aplastic apml classification clots coagulation comparison dermatomyositis
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... APLS:PLT ↓ HEMATOLOGIC ... neoplasms - PNH ... Diagnosis #clots #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hematological: - HIT, PNH ... considered in all cases ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... deficiencies - PNH ... gangrenosum • Bacterial ... Differential #Diagnosis #hematology ... #rheumatology #
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Manifestations of DIC: • Petechiae ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... : 33% • Treatment ... with pulmonary edema ... : No • Treatment ... Transfusion #Reactions #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... myalgias, HoTN, edema ... Renal Failure Treatment ... diagnosis #management #hematology ... #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
nervous system (CNS ... mucosal bleeding (Petechial ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... Significant ↓ PLT: Petechiae ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bleeding, and petechiae ... Causes: • Constitutional ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
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