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diagnosis differential treatment dermatology syndrome sle comparison erythematosus systemic vasculitis classification dermatomyositis hemolysis hemophagocytic hlh intravascular lymphohistiocytosis oncology pharmacology product
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #neurology #rheumatology ... cerebritis #diagnosis #management
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... PSS: Sjogren syndrome ... SLE : systemic lupus ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... usually IgG) (e.g. lupus ... Extravascular #Causes ... differential #diagnosis #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
the total white blood ... during an allergic reaction ... Or Inflammatory Reactions ... Colitis and Crohn’s Disease ... #hematology #basophils
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... deficiencies - PNH ... fever • Drug reactions ... Differential #Diagnosis #hematology ... #rheumatology #
Consolidation is synonymous with airspace disease. When you think of the causes of consolidation, think of 'what
with airspace disease ... you think of the causes ... Is it pus, edema ... , blood or tumor ... cells (Table on
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
intake) • Target blood ... Insufficient blood ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus ... #management
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
AIHA, Transfusion reactions ... , Drugs, Liver Disease ... , PNH 3) Internal ... - Peripheral Blood ... Differential #Diagnosis #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... Positive in 60-80% of cases ... Evolution: Chronic disease ... #Summary #rheumatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
of high parity blood ... without other cause ... with pulmonary edema ... #hematology #diagnosis ... #comparison #table
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