28 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... • Risks: infection ... transformation to acute leukemia ... #treatment #hematology ... #oncology
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
for Standard-Risk ... Consolidation & CNS ... Cytarabine #ALL ... #oncology #pediatrics ... #peds #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... Transformation: • Complication ... #Hematology #Oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
neutropenic fever) Complications ... to MDS or acute leukemia ... • Associated PNH ... Anemia #diagnosis #management ... #treatment #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Most common leukemia ... thrombocytopenia Complications ... chemotherapy for low-risk ... #oncology #hematology ... hemeonc #diagnosis #management
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
patients at high risk ... also balance the risk ... VTE and bleeding complications ... Anticoagulation #Management ... #Hematology #Oncology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
functional ID) Treatment ... showed reduced risk ... composite endpoint of all-cause ... heartfailure #diagnosis #management ... #cardiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
of hospitalized pts ... Lowest Risk: Tetracyclines ... - produced by all ... CT A/P: Assess complications ... KUB ↓↓Sens for complications
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... Attempt if high risk ... APML #diagnosis #management ... #hematology #oncology