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oncology sle syndrome differential erythematosus dermatology disease druginduced fungal hemeonc neurology summary aplastic autoimmune cardiology cell chronic cll hemolytic infectiousdiseases
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... autoantibodies that will cause ... #rheumatology # ... cerebritis #diagnosis ... #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... life-threatening • Treatment ... #Diagnosis #Management ... #Summary #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... • Risks: infection ... #Management #treatment ... #hematology #oncology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
1) DIAGNOSE AIHA ... 2) LOOK FOR a cause ... → Systematic screening ... #diagnosis #management ... #treatment #rheumatology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Diagnosis: • Pancytopenia ... Treatment: • Consider ... • Associated PNH ... #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
with leukopenia, anemia ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... months to years) Systemic ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Workup History ... l MD SOAP) - Risks ... changes), high MCV anemia ... #Causes #Workup ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... hemoglobinuria (PNH ... usually IgG) (e.g. lupus ... #hematology #anemia
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