10 results
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Alwavs Repeat Blood ... while drawing blood ... ischemia-induced RBC ... hemolysis) • RBC ... potassium #high #pathophysiology
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Decreased renal blood ... Diuretics -> Decreased blood ... Prostaglandins #Pharmacology ... #Pathophysiology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... shape, HbS induces RBC ... This leads to RBC ... obstructing and reducing blood ... SickleCell #Disease #Pathophysiology
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
circumferential constriction ... limb -> Local blood ... reflexively try Incr to blood ... pools outside the blood ... CompartmentSyndrome #ACS #pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Benyzlpenicillin, blood ... differential #diagnosis #pathophysiology ... #pharmacology #
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
pressure in the blood ... potent effect on blood ... #Differential #Pharmacology ... #Pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... hydration • RBC
Erythropoiesis (RBC Production and Maturation)

Pluripotent hematopoietic stem cell → Proerythroblast (a.k.a. pronormoblast) → Erythroblast (a.k.a. normoblast)
Erythropoiesis (RBC ... marrow, 1 day in blood ... Erythropoiesis #RBC ... Maturation #hematology #pathophysiology
Compartment Syndrome Pearls
A vicious cycle of increased pressure within a facial compartment leading to compression of
Pathophysiology: ... perfusion pressure → Blood ... remove anything constrictive ... diagnosis #management #pathophysiology
Hepatopulmonary Syndrome - Illness Script
HPS is a pulmonary disorder of chronic liver disease characterized by a
abnormalities PATHOPHYSIOLOGY ... overperfusion + decreased RBC ... shunting causes mixed blood