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diagnosis pocus management ultrasound cardiology echocardiogram differential video physicalexam radiology pulmonary rheumatology causes radiologyassistant treatment msk pediatrics neurology workup peds
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... lupus (90%) Anti-SSA ... Anti-Ribo-P 5-15% If SLE ... is clinically suspected
Parasternal Short-Axis (PSSA) view with right ventricle (RV), circular left ventricle (LV), and papillary muscles #Clinical
Parasternal Short-Axis (PSSA ... papillary muscles #Clinical
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Diffuse) Anti-Sm - SLE ... Anti-SSA (Ro),
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
activity Anti-Ro/SSA ... manifestations • Neonatal SLE ... dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - SLE ... pattern: - SjS, SLE ... Sm/RNP, Scl-70, SSA ... -52 (Ro52), SSA- ... Speckled: - SLE
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Anti-ENA - Rare (SSA ... 40, F:M 9:1 • Clinical ... are evocative of SLE ... management of SLE
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus (SLE ... Anti-Smith, Anti-Ro (SSA ... Syndrome: Anti-Ro (SSA
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... rheumatoid arthritis SLE
Clinical Manifestations of Systemic Lupus Erythematosus (SLE) #Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Clinical Manifestations ... Erythematosus (SLE ... Erythematosus #SLE
LVOTO due to SAM on POCUS Echocardiogram Septic patient after IV fluids and initiation of Levophed. Worsening
PSLA shown. ... Repeat PSLA. ... Cardiology #PLAX #clinical
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