13 results
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
Syndrome (IRIS) ... - Pathophysiology ... factors: - Low CD4 ... Restoration of exuberant pathogen-specific ... #Syndrome #IRIS
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory ... with exaggerated inflammatory ... depend on the pathogen ... involved Pathogens ... unintentional weight loss, nausea
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... Artifact (redo CBC ... Acute or Chronic Inflammatory ... #Causes #Hematology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic Algorithm ... Pathophysiology: ... the epidermis 2) Inflammatory ... Causes: 1) Exfoliative ... Erythroderma #Nikolsky #Algorithm
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Differential Diagnosis Algorithm ... : - Systemic Inflammatory ... Lymphocytic Leukemia (CBC ... #Causes #Hematology
Upper and Lower Causes of GI Bleed
Upper:
 • Esophagus: Tear (Mallory Weiss, Boerhaave syndrome), Variceal, Esophagitis,
Upper and Lower Causes ... Mesenteric ischemia • Inflammatory ... , Radiation CMC ... differential #diagnosis #Causes ... #algorithm
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
reactivation of latent pathogens ... • IRIS might ... present in 15% of cases ... Demyelinating disease caused ... patients with IRIS
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... Prodrome: pruritic, inflammatory ... - Erosions and crusts ... not feasible CMC
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... production of pro-inflammatory ... Drugs, Unknown cause ... 100 mg/m2) : in case
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... Diagnosis: • CBC ... Lung Abscess Pathogens ... #differential #causes