12 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... uremic syndrome (HUS ... #Hemolytic #Intravascular ... #Causes #differential ... #diagnosis #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... of schistocytes ... : • Thrombotic ... microangiopathy ... diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Hemolysis - Differential ... Diagnosis Algorithm ... Shearing • MAHA ... (TTP, DIC, HUS) ... Differential #Diagnosis
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
and laboratory diagnosis ... blue arrow) - schistocytes ... as disseminated intravascular ... @mjcascio #MAHA ... #Hematology #Pathology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy ... (TMA) - Differential ... Diagnosis Table ... #TMA #hematology ... diagnosis #HUS
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Approach to Thrombotic ... Microangiopathy ... (TMA) - Differential ... likely: • Smear: schistocytes ... #Algorithm #hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... Often hard to differentiate ... #Microangiopathy ... thrombocytopenia #Comparison #Diagnosis ... #Table #Hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
- Differential ... - Disseminated intravascular ... PNH - HIT - MAHA ... : TTP, HUS, DIC ... #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... IVIG infusion Intravascular ... Causes: • MAHA ... : TTP, HUS, DIC,
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... DDX: • TMA’s (HUS ... TTP/DITMA) - MAHA ... - MAHA: TTP/HUS ... #Coagulation #diagnosis