17 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antibody) and ANCA ... lupus erythematosus ... in drug-induced SLE ... Jcortesizaguirr #ANA ... antibodies #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antibody refers ... Positive ANAAutoimmune ... (SLE), Systemic ... (SLE), Systemic ... #patterns #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... Workup: - ANA ... #lupus #Systemic ... #Summary #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
least 2 joints • Neurologic ... pericarditis • Hematologic ... Thrombocytopenia, Autoimmune ... #Systemic #Lupus ... Erythematosus #diagnosis #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
Criteria - Systemic ... SEROSITIS - RENAL - NEUROLOGIC ... IMMUNOLOGIC CRITERIA - ANA ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... months to years) Systemic ... Workup: - ANA ... #table #rheumatology ... #diagnosis #management
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
underlying autoimmune ... treatment can prevent ... Inflammatory causes ... lupus erythematosus ... spectrum disorder • ANCA-associated
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... autoantibodies that will cause ... #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... severe disease Treatment ... diagnosis #rheumatology ... #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... lupus erythematosus ... LFT • ESR • ANA ... SLE) • Urinalysis ... differential #diagnosis #rheumatology