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algorithm anemia management thrombocytosis arthritis classification extravascular hemolysis intravascular oncology pain approach calculation common cvid gravis hepatitis hodgkins hypogammaglobulinemia immunodeficiency
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute infection ... iron deficiency, hemolysis ... disorders (e.g. autoimmune ... #Diagnosis #Causes ... #hematology #secondary
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... Diagnosis Algorithm ... circulation - Infections ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Diagnosis Algorithm ... Myelofibrosis Infectious ... effect following treatment ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Rebound effect from treatment ... : Chronic infections ... #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... Infection) High ... #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
: Autoimmune, Microangiopathic ... hemolytic anemia ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... Like in this case ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... Diagnosis Framework ... weeks) Can Be Caused ... #Diagnosis #MSK ... #rheumatology #
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... Diagnosis Neonate ... hypertension and/or drug treatment ... #diagnosis #causes ... #hematology
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