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algorithm aplastic cll lymphocytic mds myelodysplastic purpura workup arteritis bruising classification coagulation common cvid dermatology dic diffuse disorders disseminated essential
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Differential Diagnosis ... Reactive: • Anemia ... Myeloid Leukemia ... Diagnosis #causes ... #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Myelogenous Leukemia ... Myelofibrosis Infectious ... Iron deficiency anemia ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... : Chronic infections ... #Platelets #Differential ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... ): • Acute infection ... myeloid leukemia ... Diagnosis #Causes ... #hematology #secondary
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Diagnosis Algorithm ... Age > 50 • Chronic ... #Causes #Hematology ... #Oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... Vasculitis • Infection ... #Causes #Hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
: • Recurrent infections ... bleeding from low platelets ... to MDS or acute leukemia ... #diagnosis #management ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... risk-stratification • Risks: infection ... transformation to acute leukemia ... #Management #treatment ... #hematology #oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... procedures - Infection ... changes), high MCV anemia ... Diagnosis #Causes ... #Workup #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... or thrombocytopenia ... Complications: 1) Infection ... #oncology #hematology ... #management
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