17 results
oncology anemia management algorithm mds myelodysplastic purpura thrombocytopenia agglutinin ascites bruising cryofibrinogenemia dermatology disease extravascular hemolysis hodgkins intravascular lymphoma monoclonal
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... uremic syndrome ... #differential # ... diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... : Rheumatologic, ... Vasculitides, IBD ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... • Infection ... #Causes #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... • AIHA: warm, cold ... #Diagnosis #causes ... #classification ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... DIC/TTP/HUS - Hemolytic ... #Diagnosis #hematology ... #rheumatology #
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... : 70 years old, ... ~10,000 new cases ... risk-stratification • Risks: infection ... #hematology #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Agglutinin Syndrome ... Diagnosis: • hemolytic ... younger pts) Differential ... #anemia #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - Hepatitis, eosinophilic ... anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
SAAG < 1.1 g/dL) Infections ... Mediterranean fever - Vasculitis ... peritonitis - Eosinophilic ... #diagnosis #differential ... #hepatology #SAAG
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... hypertension and/or drug treatment ... white blood cell aplasia ... #diagnosis #causes ... #hematology
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