17 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Diagnosis Framework ... Myeloproliferative Disorders ... Colitis and Crohn’s Disease ... #hematology #basophils
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
/ Bruising - Differential ... Diagnosis Algorithm ... #Bleeding #Bruising ... Diagnosis #Algorithm ... #Causes #Hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Diagnosis Algorithm ... /bleeding, fatigue ... #Diagnosis #Algorithm ... #hematology #WBC ... #Leukemoid
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... PLT: Petechiae, bruising ... -> Invade Skin: ... #Hematology #Oncology ... #Diagnosis
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
disorder Clinical ... • Easy bruising ... • Skin bleeding ... factor VIII) Treatment ... #Diagnosis #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Diagnosis Algorithm ... • Rheumatic disorders ... • Celiac disease ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Diagnosis Algorithm ... • Lymphoma • Leukemia ... Myeloproliferative disorders ... #Diagnosis #Algorithm ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... lymphoproliferative disorders ... microglobulin Treatment ... #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... thalassemia, S Lepore • Basophilic ... Consider RBC membrane disorder ... #Diagnosis #Algorithm ... #workup #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Bleeding and Bruising ... Hemostasis - Differential ... Diagnosis Framework ... gingivitis or gingival leukemic ... Diagnosis #Hematology