29 results
differential oncology syndrome anemia bleeding chronic classification lymphocytic mds myelodysplastic pathophysiology abnormal antinxp2 antinxp2dm aplastic aptt arterial basophilia basophils cancer
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Diagnosis Algorithm ... • Disseminated Intravascular ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... coagulation (DIC ... ) (e.g. lupus, CLL ... lymphoproliferative disorders ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... • Rheumatic disorders ... • Celiac disease ... #Algorithm #Causes ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
• Lymphoma • Leukemia ... Myeloproliferative disorders ... • Sickle Cell ... #Algorithm #Causes ... #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
inherited bleeding disorder ... Clinical • Easy bruising ... • Skin bleeding ... factor VIII) Treatment ... #Diagnosis #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... PLT: Petechiae, bruising ... -> Invade Skin: ... #Hematology #Oncology ... #Diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... , coagulation disorders ... disorders CAUSES ... #hematology #rheumatology ... #nonpalpable #dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... lymphoproliferative disorders ... microglobulin Treatment ... #oncology #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
- Differential Diagnosis ... Myeloproliferative Disorders ... Colitis and Crohn’s Disease ... #Differential #Diagnosis ... #causes #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... transformation to acute leukemia ... Allogeneic stem cell ... #Management #treatment ... #hematology #oncology
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