32 results
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
D Discoid Rash ... Pleuritis) H Hematologic ... Arthritis R Renal ... #IMDAMNSHARP #sle ... erythematosus #rheumatology
Lupus Nephritis Classification Algorithm

#Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Classification Algorithm ... Classification #Algorithm ... #diagnosis #differential ... #types #rheumatology ... #nephrology #renal
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
Suggested algorithm ... CBC, complete blood ... MGUS #Followup #algorithm ... #diagnosis #management ... #hematology #multiplemyeloma
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... Insufficient blood ... Special cases (e.g. renal ... #rheumatology # ... levels #lupus #management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Photosensitivity, Butterfly rash ... Abdominal pain (20%) Renal ... Glomerulonephritis Myositis(5%) Blood ... signs #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Management Summary ... Manifestations: Malar rash ... Erythematosus #Diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
severe disease & renal ... • Specific for SLE ... #Summary #diagnosis ... #rheumatology # ... management
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased ... RA, SLE, PRV, Chronic ... Reticulocytosis • Renal ... #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... thrombosis and/or blood-brain ... #CNS #neurology ... #rheumatology # ... #management #treatment
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... onset [33-74%] • Blood ... Dermatomyositis #rheumatology ... #dermatology #diagnosis