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differential management algorithm coagulation prolonged syndrome disorders erythrocytosis lupus oncology pt pv sle summary vasculitis workup activation adultonset aggregometry bleeding
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
to Evaluate an Abnormal ... Is a Systemic Disease ... to identify the cause ... #diagnosis #hematology ... mixing #studies #PTT
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... INR), Prolonged PTT ... PTT, Normal PT ... #Differential #Diagnosis ... #Hematology #coagulation
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... - Differential Diagnosis ... Disease #Polycythemia ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... thrombocytosis • Polycythemia ... disorders • Celiac disease ... effect following treatment ... #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Von Willebrand Disease ... aPTT (prolonged ... factor VIII) Treatment ... VonWillebrand #Disease ... #Diagnosis #Hematology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
- Acquired Causes ... Hypoxia-driven: Cardiac/pulmonary ... disease, Smoking ... ), TEMPI (VEGF normal ... #Algorithm #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... #Hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
screening for disease ... ) • aPTT is prolonged ... mixing study (aPTT ... mild cases) • ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT/PTT ... PT/INR: ↑ • PTT ... • Severe Liver Disease ... #causes #treatment ... #management #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... Better call hematology ... about secondary causes ... As with many disease ... Algorithm #workup #hematology
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