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rheumatology ana antinuclear testing causes erythematosus lupus patterns systemic autoantibodies laboratory nuclear types vasculitis workup acidosis anca antibodies antineutrophil arthritis
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... (anti-nuclear antibody ... Antiphospholipid Antibody ... perinuclear), C-ANCA (cytoplasmic ... #diagnosis #associations
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... - Nuclear and Cytoplasmic ... #Antinuclear #Antibody ... #Patterns #differential ... #diagnosis #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... pericarditis • Hematologic ... #EULARACR #Classification ... #Criteria #SLE ... Erythematosus #diagnosis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic ... in drug-induced SLE ... scleroderma) - Anti-Scl ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
antineutrophil cytoplasmic ... antibody. ... #Diagnosis #Rheumatology ... #Differential # ... Medium #Large #Classification
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... Testing Cytoplasmic ... #Testing #Cytoplasmic ... #Patterns #differential ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... involvement 3% SLE-Related ... ) 30-45% Differential ... Lupusreference #SLE ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... test, ANA (e.g., SLE ... changes), high MCV anemia ... not required in all
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... rubella titer, ACE ... (to support a diagnosis ... laboratory #workup #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... Antineutrophil cytoplasmic ... antibody) associated ... #types #classification ... #rheumatology #
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