25 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... in drug-induced SLE ... scleroderma) - Anti-Scl ... antibodies #diagnosis #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Disease Associations ANA ... Graves' disease c-ANCA ... Wegener's granulomatosis ... p-ANCA - Vasculitis ... diagnosis #table #rheumatology
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (MPA) - ANCA ... Algorithm - ACR ... Polyangiitis #MPA #ANCA ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Active
Polyangiitis (EGPA) - ANCA ... Algorithm - ACR ... #Polyangiitis #ANCA ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... Workup: - ANA ... #comparison #table ... #rheumatology # ... diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Management Summary ... Workup: - ANA ... 50-60% - pANCA ... life-threatening • Treatment ... #Summary #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... glomerulonephritis - Granulomatous ... VESSEL VASCULITIS (Granulomatous ... SLE) • Urinalysis ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Antinuclear (ANA ... severe disease Treatment ... Ann Marie Kumfer ... Summary #diagnosis #rheumatology ... #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... diseases, such as SLE ... Pauci Immune (ANCA ... #Diagnosis #Rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... pericarditis (search ANA ... pleurisy (search ANA ... and aPL) 9) Unexplained ... erythematosus #rheumatology