19 results
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
Renin-Angiotensin-Aldosterone ... Antagonists), all ... diuretic, which ... , just like all ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... - Loop diuretics ... , Thiazide diuretics ... differential #algorithm #diagnosis ... #nephrology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Synthesis of aldosterone ... Trimethoprim) • Aldosterone ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
- Differential Diagnosis ... • HTN, High Aldosterone ... Loop and thiazide diuretics ... Algorithm #causes #potassium ... #low #nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... Piretanide Potassium ... #Pharmacology # ... nephrology #conversion
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... Alkalosis: Emesis, Diuretics ... #Hypokalemia #diagnosis ... #differential #potassium ... #nephrology #low
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential Diagnosis ... >20 mEq/24 h - Diuretics ... #Differential #Diagnosis ... #Algorithm #nephrology ... #causes #low #potassium
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... Inhibitors of Na+K+2Cl ... Receptor Antagonists (Aldosterone ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... - ↓ Renin/Aldosterone ... ± Renin/Aldosterone ... Ca-gluconate or 1g CaCl ... #potassium #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
loop or thiazide diuretics ... pressure: Active diuretic ... of sodium and potassium ... urine #Algorithm #nephrology ... #differential #diagnosis