21 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Drugs Implicated in Hemolytic Anemia
 • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Drugs Implicated ... Anemia • Hapten (Drug ... Hemolytic #Anemia #differential ... #diagnosis #pharmacology ... #table
Fibrinolysis. 
Fibrinolysis occurs when plasminogen is activated to plasmin under the influence of factors such as
and urokinase act ... thrornbolytic drugs ... anticoagulant drugs ... Fibrinolysis #Pathway #Pathophysiology ... #Plasminogen #Pharmacology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Aldosterone Release: ACE ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... Drug-induced edema ... Medication #Causes #Differential ... #Pharmacology # ... Pathophysiology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Diagnostic Algorithm Pathophysiology ... : - Catch-all term ... - Pathophysiology ... anti-convulsant or sulfa-drug ... Targetoid #Algorithm #Differential
The 8 A’s — drugs that interact with warfarin
Antibiotics 
 - Most agents, but especially co-trimoxazole,
The 8 A’s — drugs ... Anti-inflammatory agents - All ... Warfarin #Coumadin #Drug ... #Interactions #Table ... Mnemonic #8As #Pharmacology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... • Intravenous Drug ... Pregnancy • Drugs ... considered in all ... Venous #Arterial #pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
filtered Na+/K+/Cl ... filtered Na+ and Cl ... Segments #Function #Pathophysiology ... #Tubules #Table ... #Pharmacology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Drugs (Statins), ... Dermatomyositis) AKI - Pathophysiology ... per day until stable ... Rhabdomyolysis #Differential