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diagnosis hematology algorithm causes signs arteritis giantcell platelets symptoms temporal vasculitis blood clinical cutaneous dermpath disorders hemolytic lesions management manifestations
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... malignancies • Anemia ... #Differential # ... Diagnosis #Causes #hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - ... Differential Diagnosis ... Reactive: • Anemia ... #Differential # ... causes #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... Iron deficiency anemia ... #Differential # ... Algorithm #Causes #Hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential ... Diagnosis Algorithm Signs ... #Differential # ... Diagnosis #Algorithm #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... Platelet Count - Differential ... → Refer to hematology ... hemolysis, deficiency anemia ... #Platelets #Differential
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
expression - Age: GCA ... yrs old; F>M Signs ... ESR - Thrombocytosis ... - Normocytic Anemia ... Pathophysiology #Diagnosis #Signs
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Pelger-Huet, Macrocytic anemia ... PV), Essential Thrombocytosis ... Blood #Disorders #hematology ... #Markers #Differential
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... systemic complaints- anemia ... , thrombocytosis ... #Temporal #Signs
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
vasculitis (5%): PAN > GPA ... Vasculitis #dermpath #dermatology ... #semiology #signs ... pathology #lesions #differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... vasculitis - GPA ... Vasculopathy #Purpura #Differential ... #nonpalpable #dermatology
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