14 results
diagnosis differential hematology erythematosus management sle systemic causes hemolysis anemia classification extravascular hemolytic intravascular summary treatment activation algorithm autoantibodies comparison
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Lupus (DIL): ... & NPSLE rare, Malar ... Lupusreference #druginduced ... #table #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... : -10% of all lupus ... & NPSLE rare, Malar ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
MAHA: TTP, HUS, DIC ... Transfusion reactions, Drug-associated ... Membrane Defects, Drugs ... Infections/toxins: Malaria ... Differential #Diagnosis #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar ... , oral ulcers, Lupus ... of SLE versus DIL ... Management #Summary #rheumatology
Lupus Classification Spontaneous Lupus - Cutaneous Lupus Erythematosus (CLE) - Systemic Lupus Erythematosus Drug-Induced Lupus - Drug-Induced
Erythematosus Drug-Induced ... Lupus - Drug-Induced ... CLE (SCLE-DIL) ... - Drug-Induced ... erythematosus #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation (DIC ... usually IgG) (e.g. lupus ... infection) - Drugs ... • Infections: Malaria ... differential #diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Production: - Drugs ... - Parasitic: Malaria ... Microangiopathy: DIC ... Diagnosis #Framework #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
delayed HTR • Drug-induced ... Infections • Malaria ... • PNH • Drug-induced ... • MAHA (TTP, DIC ... Algorithm #Causes #Hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Arthritis 69% - Malar ... Mimickers: Drug-induced ... lupus, Cutaneous ... #differential #rheumatology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
AIHA: warm, cold, drug ... Bartonella, Babesia, Malaria ... MAHA: TTP, HUS, DIC ... classification #hematology
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