31 results
hematology causes anemia erythematosus joint management sle algorithm arthritis classification disease hemolysis signs symptoms systemic workup blood bruising comparison extravascular
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... usually IgG) (e.g. lupus ... • Infections: Malaria ... Extravascular #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... Diagnosis Algorithm ... Infections • Malaria ... #Diagnosis #Algorithm ... #Causes #Hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... Lymphadenopathies 7% - Hemolytic ... (aPL) 30-45% Differential ... Diagnosis and Lupus ... #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... suspected, consider malaria ... #Anemia #Differential ... #workup #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... Bartonella, Babesia, Malaria ... #Diagnosis #causes ... classification #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... Diagnosis Congenital ... Diseases: • Systemic lupus ... Antibody-mediated hemolysis ... #Diagnosis #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Splenomegaly - Differential ... Diagnosis Algorithm ... Inflammatory • Systemic Lupus ... Serum Sickness Hemolytic ... #Causes #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Infections/toxins: Malaria ... #Differential # ... Diagnosis #hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
B19 infection Malar ... lesions • Discoid lupus ... dermatology #joint #pain ... #skin #rashes #differential ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... lesions Abdominal pain ... Thrombocytopenia #Lupus ... signs #symptoms #diagnosis ... #rheumatology
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