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hematology diagnosis differential management bleeding bruising pathophysiology teg thrombocytopenia thromboelastogram thromboelastography aflp causes comparison hellp hemostasis obstetrics pregnancy ttphus warfarin
Hemostasis Physiology The blood's response to blood vessel injury can be viewed as four interrelated steps. Roman
numerals refer to coagulation ... diphosphate; PF-3, platelet ... Pathophysiology #Coagulation ... #Cascade #Hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... cascade is shown ... multicomponent complexes on platelets ... #Coagulation #Cascade ... #platelet #thrombin
Thromboelastogram Interpretation Reaction Time (R Value): - Time till initiation of fibrin clot - Treatment: FFP, protamine K
Thromboelastogram Interpretation ... representing thrombin-platelet ... - Treatment: Platelets ... Thromboelastogram #TEG #Interpretation ... Thromboelastography #diagnosis #coagulation
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Differential Diagnosis Algorithm ... vs Acquired • Platelet ... Qualitative • Coagulation ... Differential #Diagnosis #Algorithm
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... pheresis - Platelets ... proteins, all coagulation ... Hematology #Management #Table
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Differential Diagnosis Algorithm ... Sequestration Disordered Platelet ... • Vasculitis Coagulation ... deficiencies Coagulation ... Differential #Diagnosis #Algorithm
THROMBOELASTOGRAPHY (TEG) General Principle • A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
problems with coagulation ... cascade and platelet ... CriticalCare #Hematology #Interpretation
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
presents with coagulation ... Liver tests, Low Platelets ... pregnancy * Severe coagulation ... Diagnosis #Comparison #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
presents with coagulation ... Liver tests, Low Platelets ... pregnancy * Severe coagulation ... hematology #diagnosis #table
Thromboelastography (trademarked as TEG) • Graphical representation of the fibrin polymerization process • Point-of-care anti-coagulation monitoring
Point-of-care anti-coagulation ... routine transfusion algorithms ... amplitude • If ↓ → platelet ... deficiency → give platelets ... Thromboelastogram #TEG #interpretation
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