37 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... #Defects #comparison ... differential #diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Differential Diagnosis Algorithm ... Sequestration Disordered Platelet ... • Vasculitis Coagulation ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
numerals refer to coagulation ... diphosphate; PF-3, platelet ... Pathophysiology #Coagulation ... #Cascade #Hematology
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
representing thrombin-platelet ... - Treatment: Platelets ... Thromboelastography #diagnosis #coagulation ... #hematology
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... DrEricStrong #Algorithm ... #Coagulation #Abnormal ... APTT #Laboratory #Hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
presents with coagulation ... Liver tests, Low Platelets ... pregnancy * Severe coagulation ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... pheresis - Platelets ... proteins, all coagulation ... Contents #Volume #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
presents with coagulation ... Liver tests, Low Platelets ... pregnancy * Severe coagulation ... AFLP #obstetrics #hematology ... diagnosis #table #comparison
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Differential Diagnosis Algorithm ... Thrombocytosis #Platelets ... Differential #Diagnosis #Algorithm ... #hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... Features of hematologic ... anemia, ↑ MCV, ↑/↓ platelets ... Differential #Diagnosis #Algorithm ... #hematology #WBC