15 results
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
Thromboelastogram ... representing thrombin-platelet ... - Treatment: Platelets ... rishikumarmd #Thromboelastogram ... Thromboelastography #diagnosis #coagulation
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Bleeding and Bruising ... vs Acquired • Platelet ... Qualitative • Coagulation ... vs Acquired #Bleeding
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Sequestration Disordered Platelet ... • Vasculitis Coagulation ... deficiencies Coagulation ... #Bleeding #Bruising
Thresholds for Transfusion of Platelets in Adults
Major surgery or invasive procedure, no active bleeding - 
≤
Transfusion of Platelets ... procedure, no active bleeding ... Surgery with active bleeding ... 100 (rarely) Stable ... #Management #Platelets
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation ... Findings: • Bleeding ... Findings: • Bleeding ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... pheresis - Platelets ... proteins, all coagulation ... Hematology #Management #Table
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
Bleeding manifestations ... are typical of coagulation ... lowest levels Platelet ... ability to bind platelets ... Measurement of coagulation
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
presents with coagulation ... Liver tests, Low Platelets ... pregnancy * Severe coagulation ... Diagnosis #Comparison #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
presents with coagulation ... Liver tests, Low Platelets ... pregnancy * Severe coagulation ... hematology #diagnosis #table
Thromboelastography (trademarked as TEG)
 • Graphical representation of the fibrin polymerization process
 • Point-of-care anti-coagulation monitoring
Point-of-care anti-coagulation ... amplitude • If ↓ → platelet ... deficiency → give platelets ... Thromboelastography #Thromboelastogram