12 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... #Defects #comparison ... #table #differential
Thresholds for Transfusion of Platelets in Adults
Major surgery or invasive procedure, no active bleeding - 
≤
Thresholds for Transfusion ... of Platelets in ... 100 (rarely) Stable ... #Management #Platelets ... #Transfusion #Plateletpheresis
â–º
Thromboelastography (trademarked as TEG)
 • Graphical representation of the fibrin polymerization process
 • Point-of-care anti-coagulation monitoring
determining if transfusion ... algorithms and ... reduce number of transfusions ... amplitude • If ↓ → platelet ... deficiency → give platelets
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Differential Diagnosis Algorithm ... vs Acquired • Platelet ... Differential #Diagnosis #Algorithm ... #pathophysiology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... Sulfate • If platelets ... 100: consider platelet ... transfusion 4. ... Pressure #ICP #Pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
TRALI vs TACO - Transfusion ... blood donor • Pathophysiology ... • Pathophysiology ... hematology #diagnosis #comparison ... #table
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
incompatible blood transfusion ... protein C and S Pathophysiology ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... hydration • RBC transfusion
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Liver tests, Low Platelets ... hematology #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Liver tests, Low Platelets ... Hematology #Diagnosis #Comparison ... #Table
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
demonstration of platelet ... #Endocarditis #comparison ... Marantic #diagnosis #table