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Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes ... of Acute Liver Injury ... #Diagnosis #Hepatology ... Injury #Causes # ... Incidence #Table #Failure
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
Causes of Acute ... Kidney Injury ( ... • Sepsis • Blood ... #Kidney #Injury ... #Differential #Nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Common causes of ... Acute Kidney Injury ... HEMODYNAMIC • Cardiac failure ... Tubular Injury/ ... NephroP #AKI #causes
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Kidney Failure ... Drug-Induced Liver Injury ... EmoryGastroHep #ACLF #Acute ... #Cirrhosis #Hepatology
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... Dehydration • Heart failure ... syndrome) • Liver failure ... tubular necrosis (causes ... #Kidney #Injury
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Acute Kidney Injury ... Diuretics if heart failure ... Glomerular (red blood ... eosinophils/white blood ... #Kidney #Injury
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Criteria HRS-AKI (Acute ... injury: No proteinuria ... HRS-NAKI (Non-Acute ... - No other cause ... HRSAKI #HRSNAKI #hepatology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... Investigations: full blood ... osmolarity If cause ... #Kidney #Injury ... #causes
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
ascites removed • Acute ... kidney injury ( ... ≥ 1B) - 1 g/kg for ... 1st day, 1g/kg ... Cirrhosis #treatment #hepatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
the peripheral blood ... deficiencies: Chronic kidney ... • Bone marrow failure ... Index > 3: • Acute ... Production #Index #hematology