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diagnosis hematology management differential algorithm workup autoimmune causes chronic cll leukemia lymphocytic mds myelodysplastic warm @dharsaty aiha antibody aplastic ascorbicacid
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Reticulocytosis/polychromasia ... breakdown • Anaemia ... haptogbbulin #Hemolysis ... #Hemolytic #Anemia
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... lncreased WBCs - Polychromatic ... Bleed • Hemolysis ... - Polychromatic ... Microangiopathic Hemolytic
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... lead poisoning • Polychromasia ... decrease - PNH • Polychromasia ... ARUPConsult @ARUPLabs #Hemolytic ... #Anemia #Differential
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Anemia Warm Autoimmune ... Hemolytic Anemia ... Spherocytes • Treatment ... Anemia: • Mechanism ... • Treatment: Warm
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Antibody Autoimmune Hemolytic ... Anemia 1) DIAGNOSE ... AIHA • Anemia ... #Anemia #diagnosis ... #management #treatment
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... > 10, no more hemolysis ... #Anemia #AIHA # ... Treatment #management
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
right photo above polychromasia ... to be seen in hemolytic ... anemias, especially ... microangiopathic hemolytic ... anemia in which
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion
metastases Treatment ... - Cytopenias (anemia ... differential #diagnosis #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Immune Aplastic Anemia ... Treatment: ... #oncology #hematology
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