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Daptomycin - Antibiotics Class Overview Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... only covers Gram positives ... MRSA bacteremia/endocarditis ... cidal nature) #Pharmacology ... #Antibiotics #Review
Aminoglycosides - Antibiotics Class Overview Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV) Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... Gram positives ( ... effect (mainly in endocarditis ... #Pharmacology #Antibiotics ... #Review #Overview
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview Mechanism: Glycopeptide - inhibits cell wall synthesis
lipoglycopeptide antibiotics ... ) - Antibiotics ... Used for: all sorts ... #Pharmacology #Antibiotics ... #Review #Overview
Tigecycline (IV) - Antibiotics Class Overview Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic). Only
Tigecycline (IV) - Antibiotics ... coverage - Gram positive ... #Pharmacology #Antibiotics ... #Review #Overview
Carbapenems - Antibiotics Class Overview Imipenem/Cilastin, Meropenem, Ertapenem, Doripenem Spectrum: Broadest spectrum antibiotics, cover Gram positive, Gram
Carbapenems - Antibiotics ... Broadest spectrum antibiotics ... , cover Gram positive ... infections #Pharmacology ... #Antibiotics #Review
Synercid (Quinupristin/Dalfopristin) (IV) - Antibiotics Class Overview Mechanism: “Streptogramins”– inhibits sequential steps in ribosomal synthesis Spectrum: covers MRSA
Dalfopristin) (IV) - Antibiotics ... for bacteremia/endocarditis ... #Pharmacology #Antibiotics ... #Review #Overview
Linezolid (Zyvox) (PO and IV) - Antibiotics Class Overview Mechanism: Oxazolidinone class –unique ribosomal inhibitor (acts on
(PO and IV) - Antibiotics ... covers all Gram positives ... infections #Pharmacology ... #Antibiotics #Review
Flutycosine - Antibiotics Class Overview - Mechanism: 5-FC interferes with DNA and protein synthesis. Only
Flutycosine - Antibiotics ... candidal infections (endocarditis ... #Pharmacology #Antibiotics ... #Review #Overview
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview Mechanism: binds ergosterol in membrane and
Abelcet, Ambisome - Antibiotics ... forms membrane pores ... #Pharmacology #Antibiotics ... #Review #Overview
Endocarditis - Duke Criteria - Major and Minor MAJOR CRITERIA: - Persistently +ve blood culture for
Endocarditis - Duke ... Osler's nodes, Roth spots ... rheumatoid factor - Positive ... criteria #Endocarditis ... #Major #Minor #Diagnosis
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