12 results
diagnosis management oncology differential hemeonc lysis tumor apml arterial causes classification comparison cppd dyspnea embolism emergencies fever gout hemophagocytic hepatology
Tumor lysis syndrome (TLS) - Pathophysiology: → Massive tumor cell lysis → Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... , AML, NHL → AKI ... #TumorLysis #syndrome ... #TLS #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... have fever - ACS ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation ... Syndrome in APML ... Incidence: common in APL ... ATRA treatment Pathophysiology ... diagnosis #management #hematology
Tumor Lysis Syndrome (TLS) Pathophysiology Culprits: ALL, Burkitt, SCLC Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... Culprits: ALL, ... #Tumor #Lysis #Syndrome ... #TLS #Pathophysiology
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings Classification of PCL Iniuries • Partial: Translation <
test with the knee ... positive with the knee ... diminished with the knee ... , posterolateral ... #MSK #Sports #pathophysiology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
failure - CAD/ACS ... Hepatopulmonary syndrome ... Guillain Barre - ALS ... Transverse myelitis • Hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... ): - Hematologic ... low Ca - q8 h TLS ... oncology early Differentiation ... Treatment: continue differentiating
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... considered in all ... Venous #Arterial #pathophysiology ... #hematology #differential
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... • Metabolic syndrome ... forefoot, ankles, knees ... Gout #Comparison #rheumatology
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis EPIDEMIOLOGY: PFAPA is the most common syndrome entailing
fever (FMF) PATHOPHYSIOLOGY ... occurring in some or all ... during some or all ... (CINCA/NOMID) All ... be helpful in differentiating
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