29 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... marrow) -dys- (abnormal ... only curative treatment ... #treatment #hematology ... #oncology
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
hyperkalemia) BRASH Treatment ... • Aggressive treatment ... balanced fluids" > normal ... Syndrome #diagnosis #management ... #pathophysiology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Syndrome (TLS) and Treatment ... upper limit of normal ... hypocalcemia Treatment ... TLS #diagnosis #management ... #oncology
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Treatment Schema ... mercaptopurine, Weekly oral ... given throughout treatment ... #timeline #oncology ... pediatrics #peds #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... 500 mg QD until normal ... APML #diagnosis #management ... #hematology #oncology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... (A) Suggested treatment ... DOAC, direct oral ... Anticoagulation #Management ... #Hematology #Oncology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... direct-acting oral ... direct-acting oral ... Anticoagulation #Management ... #Hematology #Oncology
Vasospastic (Prinzmetal) Angina
Definition / Epidemiology:
 • Rest angina attributed to coronary artery vasospasm.
 • Patients often
Pathophysiology: ... • Normal exercise ... tests in cath lab Treatment ... cardiology #diagnosis #management
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... ICH Management ... lidocaine, +/- pre-treatment ... Maintain Normals ... #neurosurgery #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thrombocytopenia - Normal ... + Bleeding Treatment ... - APTT < 1.5 x normal ... #management #hematology