827 results
diagnosis symptoms signs management differential nephrology cardiology endocrinology pharmacology syndrome ophthalmology algorithm clinical hematology complications causes infectiousdiseases msk lifecycle cdc
Melanoma Pathogenesis Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
repair → melanocyte proliferation ... #Pathophysiology
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
findings Mild Non-proliferative ... Moderate Non-proliferative ... spots Severe Non-proliferative ... Venous beading Proliferative ... complications #pathophysiology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
combination -> Incr proliferation ... activates hyper-proliferative ... apoptosis -> Stromal proliferation ... Hyperplasia #Prostate #Pathophysiology
Feedback Loop: Prolactin (PRL) • PRL levels exhibit diurnal, menstrual, and age-related variation • TRH has
Organs -> Promotes proliferation ... endocrinology #pathophysiology
Lower Urinary Tract Infections: Complications - Infection damages the urinary tract epithelium causing fibroblast proliferation and
causing fibroblast proliferation ... UrinaryTractInfection #LUTI #Pathophysiology
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings Predisposing Factors: - Immunocompromised, Diabetes, - Elderly, Female
parenchyma -> Bacterial proliferation ... UrinaryTractInfection #UUTI #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... Spontaneous if high proliferation
Retinopathy of Prematurity: Pathogenesis and clinical findings Increased metabolic demand of growing eye -> Excessive VEGF production ->
fibrovascular proliferation ... peds #pediatrics #pathophysiology
Hyperuricemia: Pathogenesis and Complications - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Acid Lympho-proliferative ... Hyperuricemia #Pathophysiology
Allergic Rhinitis: Pathogenesis and clinical findings 1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
), bone marrow proliferation ... Rhinitis #Rhinorrhea #pathophysiology
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