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Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
protein/Cr - Renal ... rhabdo/TLS) Causes ... and pre-renal) ... #Nephrology #Diagnosis ... #Algorithm #Causes
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
Causes of acute ... renal, and post-renal ... causes. ... Renal causes of ... #Sites #Nephrology
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Causes of Acute ... Framework Pre-Renal ... (ATN) • Glomerular ... drtonydang @CMC_IM #AKI ... #KidneyInjury #Causes
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... C3/C4, Other • ATN ... Medicine @SCVMCMed #AKI ... Differential #Diagnosis #nephrology ... #causes #algorithm
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI ... osmolarity If cause ... of AKI remains ... Kidney #Injury #AKI ... #causes
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Algorithm Extra-renal ... loss (Diarrhea) Renal ... , Renovascular HTN ... Diagnosis #Algorithm #causes ... potassium #low #nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Common causes of ... Kidney Injury AKI ... thromboembolism, renal ... Injury/Necrosis (ATN ... #causes #Acute
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Consider secondary HTN ... multi-drug resistance) Renal ... Nephritic syndrome • AKI ... #Hypertension #HTN ... #Secondary #Nephrology
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Kidney Injury (AKI ... PROBLEM ~80% of AKI ... CONSIDER INTRINSIC CAUSES ... etiologies due to ATN ... LorinskyMD #AKI
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
urinalysis, labs - Management ... biopsy - Management ... treating underlying cause ... ultrasonography - Manaqement ... Kidney #Injury #AKI