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diagnosis differential signs causes algorithm insufficiency addisons calcium management oncology pathophysiology secondary 21hydroxylasedeficiency 21ohd alkaline alp cushings diabetes diabeticketoacidosis disease
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... Immobilization Hypercalcemia ... intoxication #Hypercalcemia ... calcium #high #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism
Hypercalcemia - ... Diagnosis Algorithm Primary ... Hyperparathyroidism • Hypercalcemia ... Hypocalciuria Hypercalcemia ... Paget's Disease #Hypercalcemia
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Hypercalcemia - ... or normal): • Primary ... Hypocalciuric Hypercalcemia ... Thiazides/Lithium #Hypercalcemia ... Algorithm #causes #endocrinology
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... hormone–dependent Primary ... hypocalciuric hypercalcemia ... Jansen disease #Hypercalcemia ... Differential #Diagnosis #Endocrinology
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 Hypomagnesemia (Serum level < 1.7 mg/dL) Neuromuscular manifestations • Tremor, tetany, seizures • Weakness
dysrhythmias Hypokalemia ... • Renal potassium ... metabolism • Hypocalcemia ... Hypomagnesemia #Signs ... #Symptoms #Diagnosis
Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
Causes of Hypercalcemia ... structure-related • Primary ... hypocalciuric hypercalcemia ... Milk-alkali syndrome #Hypercalcemia ... #Causes #endocrinology
Symptoms and Signs of Hypocalcemia Muscular: Weakness, fatigue, Spasms, cramps Neurologic: Tetany, Chvostek sign, Trousseau sign, Circumoral and
Symptoms and Signs ... of Hypocalcemia ... secretion #Hypocalcemia ... #Symptoms #Signs ... #diagnosis #endocrinology
CLINICAL MANIFESTATIONS OF ADRENAL INSUFFICIENCY. Primary and secondary adrenal insufficiency: - Tiredness, weakness, mental depression
Primary and secondary ... eosinophilia Primary ... Hyperpigmentation - Hyperkalemia ... Insufficiency #Signs ... #Symptoms #Adrenal
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Primary Adrenal ... vomiting • Fatigue Signs ... Reduced libido • Signs ... addisons #disease #endocrinology ... #diagnosis #signs
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Diagnosis Algorithm Primary ... of nucleotides Primary ... • Chronic renal ... Sarcoidosis • Hypercalcemia ... Diagnosis #Algorithm #endocrinology
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