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management differential lupus oncology erythematosus signs systemic treatment workup arthritis classification disease vasculitis algorithm dermatology hemeonc leukemia thrombocytopenia antinuclear autoantibodies
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Kawasaki, Nephrotic syndrome ... Glucocorticoids, IL-1B, ATRA ... #Algorithm #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Demyelinating syndromes ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... anti-synthetase syndrome ... at diagnosis). ... Can also see mechanics ... #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... Associated - SLE ... #hematology #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Erythematosus Clinical ... Criteria CLINICAL ... IMMUNOLOGIC CRITERIA - ANA ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... Auto-Antibodies: - ANA ... Lupusreference #SLE ... autoantibodies #signs #symptoms ... #differential #rheumatology
Acute Coronary Syndrome - Diagnostic Likelihood Ratios for Symptoms and Physical Examination. Source: Fanaroff AC, Rymer
Acute Coronary Syndrome ... Ratios for Symptoms ... and Physical Examination ... Source: Fanaroff AC ... : The Rational Clinical
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution ... context of other symptoms ... likely it will be clinically ... #patterns #rheumatology ... #diagnosis #differential
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Clinical Presentation ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Clinical Features ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... #Rheumatology
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